Yes, the DefenderPad® can be used on a desk, but may not be necessary. The DefenderPad® blocks laptop EMF radiation emissions whether it it placed on a lap, a desktop, table or any other surface. When a laptop is used on a desk or table without a DefenderPad®, the laptop emissions can travel completely through. Most desks and tables do not have the capacity to shield any of the 0-10 GHz spectrum radiation emissions. However, these emissions present less risk to the body because there tends to be a fair distance between the laptop and the body legs (lower body). When one foot away for example, the danger to health risks from EMF radiation is significantly reduced.